SMARTHEART
Towards a better model for heart physiology
The SmartHeart is a 3D cardiac assay, which enables both the self-assembly and maturation of functional cardiac organoids based on cardiomyocytes derived from hiPSC as well as the acquisition of the most relevant read-outs, all in a single platform.
Explore more application notes on the SmartHeart
SPHEROID
New technologies to culture spheroids
4Dcell offers 6, 12 and 24 well plates containing hydrogel-based microwell structures specially designed for the spontaneous formation of uniform spheroids. The anti-adhesive properties of the hydrogel facilitates rapid self-assembly of cell aggregates into compact spheroids.
Explore more application notes on the Spheroid
WEBINAR – CELL MIGRATION
New technologies to study cell migration
Cell migration is an essential event involved in many physiological and pathological processes. In this webinar we present various technologies that can be employed to study cell migration in conditions that optimally mimic the in vivo microenvironment. The advantages of these tools (e.g., cell confiner, microchannels, micropatterns) over conventional cell culture methods are discussed, and practical examples are shown.
Explore more application notes on Cell Migration
WEBINAR – CELL DIFFERENTIATION
New technologies to study cell differentiation
Cells undergo differentiation as they mature and specialize in different functions. The cellular differentiation is a vital process in living organisms, regulated by mechanical and chemical stimuli. The use of appropriate lab tools to study cell differentiation in vitro is of crucial importance. In this webinar, we present several technologies (e.g., micropatterns, cell confiner, 3D hydrogels), that can be employed to improve and ensure proper cell differentiation.
Explore more application notes on Cell Differentiation
WEBINAR – WOUND HEALING
Dynamic micropatterns as a tool to study wound healing
Wound healing is a vital and complex process in physiological and pathological states. It is divided into four main stages: inflammation, growth, re-epithelialization, and remodeling. Each of these phases are mediated by several cell types, which coordinate the molecular mechanisms that ultimately lead to wound closure. In this webinar, we will discuss various technologies and scientific applications that can help studying the wound healing process (e.g. cell proliferation, migration, and contractility).
Explore more application notes on Wound Healing
TUTORIAL – MICROPATTERNING
Micropatterning – Activation
This video demonstrates the activation process for preparing glass slides before micropatterning. It highlights the importance of surface modification to enhance cell adhesion using our expert protocol. Follow along to learn more about 4Dcell micropatterns!
Explore more application notes on Micropatterns
TUTORIAL – MICROPATTERNING
Micropatterning – Peg Treatment
This video focuses on the treatment of slides with polyethylene glycol (PEG). This step is crucial for creating non-adhesive regions on the slide, which helps in patterning cells effectively using our expert protocol. Follow along to learn more about 4Dcell micropatterns!
Explore more application notes on Micropatterns
TUTORIAL – MICROPATTERNING
Micropatterning – Placing of the Cells
In this video, you’ll see how to properly plate cells onto the micropatterned slides following our expert protocol. The technique ensures that cells adhere to the desired patterns, facilitating controlled studies on cell behavior. Follow along to learn more about 4Dcell micropatterns!
Explore more application notes on Micropatterns
TUTORIAL – MICROPATTERNING
Micropatterning – Printing of the Deep UV
This video showcases the printing process using deep ultraviolet (UV) light to create precise micropatterns on glass slides. Our expert protocol explains the technical aspects and advantages of using UV for high-resolution patterning. Follow along to learn more about 4Dcell micropatterns!
Explore more application notes on Micropatterns
TUTORIAL – MICROPATTERNING
Micropatterning – Removing The Slide from The Mask
This video details the careful removal of the glass slide from the optical mask after the printing process. Proper technique is essential to maintain the integrity of the micropatterns. Follow along to learn more about 4Dcell micropatterns!
Explore more application notes on Micropatterns
TUTORIAL – MICROPATTERNING
Micropatterning – Slide Positioning on 4Dcell Mask
In this video, the focus is on accurately placing slides on the photomask to ensure optimal contact for micropatterning. This step is crucial for achieving precise patterns, as it ensures even pressure and alignment between the slides and the mask. Follow along to learn more about 4Dcell micropatterns!
Explore more application notes on Micropatterns