TECHNOLOGY
Substrates where cells are cultured contain soft or rigid microstructures in the form of open microchannels or wells. Therefore, cells can be confined in 3D environments or on the top of substrates containing this topographical features.
Many geometries of the microstructures are possible (channels/ wells dimensions vary from µm up to mm scale)
Stiffness of the substrate can be chosen from very hard (1 MPa) to very soft (< 500 Pa)
Rapid to use since cells are seeded directly on the top of features (convenient to confine non migrating cells)
Bio-functionalization with ECM proteins
Adaptable to any cell culture substrate (from Petri dishes to 96 well plates)
Compatible with high-resolution optical microscopy systems
APPLICATIONS
Cell differentiation, Cell mechanics, 3D Cell shape control, Cell migration, tissue geometry mimicry, etc
Fibroblast on micropillars substrate
Explore an example of application