Cell differentiation assay
Cell fate determination and maintenance with stiffness & its environment topography
Cell fate determination and maintenance with stiffness & its environment topography
Microgrooves
Cell organization
In standard cultures, cardiomyocytes derived from pluripotent stem cells have random shapes, are not organized thus showing immature properties.
Cardiomyocytes differentiate in substartes with topographical cues, as grooved surfaces, show natural alignment and nuclear elongation.
Difference of cell and nuclear elongation in cloned cardiac stem cells on microgrooved substrate versus common flat assays.